We've been working with looking at Lyme disease for well over 25 years in my laboratory. And what I am most interested in is the biology of this organism in the immune competent host and we use a mouse model for the most part to do that. And what comes across very clearly is that this bacteria is very good at persisting for the, literally, the lifespan of the animal. And we see this persistence in otherwise immune responsive hosts, in mice and rats and hamsters and guinea pigs and gerbils and dogs and monkeys.
Source: The Diane Rehm Show, 2-29-12